Prevention of Vascular Calcification by Polyphosphates and Nucleotides
نویسندگان
چکیده
منابع مشابه
Inflammation and Vascular Calcification Causing Effects of Oxidized HDL are Attenuated by Adiponectin in Human Vascular Smooth Muscle Cells
The role of oxidized high-density lipoprotein (oxHDL) and the protective effects of adiponectin in terms of vascular calcification is not well established. This study was conducted to investigate the effects of oxHDL with regards to inflammation and vascular calcification and to determine the protective role of adiponectin in attenuating the detrimental effects of oxHDL. Cell viability, mineral...
متن کاملMechanisms of calcification: role of collagen, polyphosphates, and phosphatase.
FLEISCH, HERBERT, AND WILLIAM F. NEUMAN. Mechanisms of calczjication: role of collagen, polyphosphates, and phosphatase. Am. J. Physiol. 200(6) : 1296-r 300. 1 g6 1 .-The nucleating properties of various collagens have been tested by determining quantitatively the minimum ion product, Ca times P, required to form calcium phosphate crystals. While most collagens require a product of 35 (mg%)2 or...
متن کاملCoexistence of anticoagulant and anti-vascular calcification activities in Kribbella sp. UTMC 267 metabolites
Thrombotic disorders increase the risk of cardiovascular/cerebrovascular complications and represent a major health problem worldwide. Anticoagulants are extensively used in treatment of these disorders. Vitamin K antagonists, like Warfarin, are frequently used in medication. Vascular calcification (VC) is a significant side-effect of vitamin K antagonists especially Warfarin. There is an urgen...
متن کاملEvaluation of Vitamin D Level and its Correlation to Vascular Calcification in Hemodialysis Patients
Introduction: Compared with the general population, hemodialysis patients are at increased risk of vascular calcification, which in turn is associated with an increased risk of mortality. Regarding the role of vitamin D in bone formation, regulation of calcium, phosphate and iPTH level and correlation of these variables in survival, this study was performed to evaluate the vitamin D serum level...
متن کاملApoptosis regulates human vascular calcification in vitro: evidence for initiation of vascular calcification by apoptotic bodies.
The mechanisms involved in the initiation of vascular calcification are not known, but matrix vesicles, the nucleation sites for calcium crystal formation in bone, are likely candidates, because similar structures have been found in calcified arteries. The regulation of matrix vesicle production is poorly understood but is thought to be associated with apoptotic cell death. In the present study...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Journal
سال: 2013
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-13-0016